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Derek Chadwick J.
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- Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized e... Подробнее
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- The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration.... Подробнее
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- This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages ... Подробнее
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- With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial res... Подробнее
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- Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibo... Подробнее
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- As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields of molecular biology, medicine, philosophy, theolog... Подробнее
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- Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality... Подробнее
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Bioactive Compounds from Plants
Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to environmental factors. The isolation and characterizat... Подробнее000
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Mucus Hypersecretion in Respiratory Disease
A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecretion. Following damage to the airway epithelium, ... Подробнее000
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Circadian Clocks and Their Adjustment
Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control circadian rhythmicity and functioning in organisms r... Подробнее000
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Postimplantation Development in the Mouse
Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patte... Подробнее000
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- The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment... Подробнее
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The Biology of Extracellular Molecular Chaperones
The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key s... Подробнее000
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Functional Anatomy of the Neuroendocrine Hypothalamus
Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into the function of the hypothalamus. Подробнее000
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Epithelial Anion Transport in Health and Disease
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, ... Подробнее000
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T Cell Subsets in Infectious and Autoimmune Diseases
T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in aut... Подробнее000
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Mechanisms and Biological Significance of Pulsatile Hormone Secretion
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes... Подробнее000
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The hERG Cardiac Potassium Channel
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound bindi... Подробнее000
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- A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary met... Подробнее
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- Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in Asia has largely been attributable to a relatively s... Подробнее
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- Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are ... Подробнее
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- Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and functio... Подробнее
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- Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the e... Подробнее
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- Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term a... Подробнее
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Oligonucleotides as Therapeutic Agents
The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRN... Подробнее000
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Somatostatin and Its Receptors
This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatost... Подробнее000
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Host-Guest Molecular Interactions
Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation of molecular assemblies containing two or more sp... Подробнее000
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Ethnobotany and the Search for New Drugs
A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to their knowledge and provision of rare plants which a... Подробнее000
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The Molecular Biology and Pathology of Elastic Tissues
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics includ... Подробнее000
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The Biosynthesis of the Tetrapyrrole Pigments
Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the structure and regulation of key enzymes along wit... Подробнее000
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Molecular Clocks and Light Signalling
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability... Подробнее000
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Mammalian TRP Channels as Molecular Targets
This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It covers the structure, function and regulation of mam... Подробнее000
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Nuclear Organization in Development and Disease
This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular ... Подробнее000
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Signalling Pathways in Acute Oxygen Sensing
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all... Подробнее000
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Purinergic Signalling in Neuron-Glia Interactions
ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry o... Подробнее000
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Gramicidin and Related Ion Channel-Forming Peptides
Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structura... Подробнее000
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- Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of h... Подробнее
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Crop Protection and Sustainable Agriculture
The increase in the world population and changes in welfare have led to an enormously expanding demand for food. In the industrialized world, food surpluses rather than shortages are a problem togethe... Подробнее000
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- Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising trend and includes research that has not yet been ... Подробнее
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The Molecular Basis of Smell and Taste Transduction
Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the lat... Подробнее000
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